OBJETIVO: Detectar a frequência e os subtipos do HPV na cérvice uterina de mulheres infectadas pelo HIV. MÉTODOS: A amostra era composta por 288 mulheres infectadas pelo HIV, recrutadas do sistema público de saúde de cinco cidades de Minas Gerais, Brasil. As mulheres foram avaliadas de agosto de 2003 a agosto de 2008. Amostras cervicais foram coletadas para análise citológica e para detecção do HPV DNA, usando a reação em cadeia de polimerase (PCR). O HPV DNA foi classificado de acordo com seu potencial oncogênico em baixo risco (tipos 6,11) e alto risco (tipos 16, 18, 31, 33, 35). Foi realizada colposcopia, seguida de biópsia cervical, quando indicada. Variáveis categóricas foram comparadas usando o teste do quiquadrado, com nível de significância estabelecido de 5%. RESULTADOS: A prevalência do HPV foi 78,8%. Os genótipos mais frequentes foram HPV-6 (63,9%) e HPV-16 (48,5%). Genótipos de HPV de alto risco foram observados em 70,5% das mulheres; de baixo risco em 71,4%; HPV de alto e baixo risco foram detectados em 55,1% das pacientes. Múltiplos genótipos de HPV foram detectados em 64,8% das pacientes; dois genótipos em 23,8%, e três em 18,9%. CONCLUSÃO: A prevalência do HPV foi alta entre mulheres infectadas pelo HIV. Múltiplos genótipos de HPV foram comuns em amostras da cérvice uterina destas mulheres

OBJECTIVE: To detect the frequency and subtypes of HPV in the uterine cervix of HIV-infected women. METHODS: Sample consisted of 288 HIV-infected women, recruited from the public health system of five cities of Minas Gerais, Brazil. Women were seen from August 2003 to August 2008. Cervical samples were collected for cytological analysis and for HPV DNA detection, using polymerase chain reaction (PCR). HPV DNA was classified according to its oncogenic potential in low risk (types 6, 11) and high risk (types 16, 18, 31, 33, 35). Colposcopy was performed, followed by cervical biopsy when necessary. Categorical variables were compared using the Chi-squared test, with a significance level established at the 5% level. RESULTS: HPV prevalence was 78.8%. Most frequent genotypes were HPV-6 (63.9%) and HPV-16 (48.5%). High-risk HPV were observed in 70.5% of the women; low-risk in 71.4%; both high and low-risk HPV were detected in 55.1% of the patients. Multiple HPV genotypes were detected in 64.8% of the patients; two genotypes in 23.8%, and three in 18.9%. CONCLUSION: HPV prevalence was high among HIV-infected women. Multiple HPV genotypes were common in samples from the uterine cervix of HIV-infected women

OBJECTIVE: To examine health care use and expenditures by Brazilians covered by private health care plans in the last four years of life. METHODS: Health plan provider enrollee files and death certificate data were used for 274 health plan beneficiaries who died in 1998, 1999, and 2000. Resources used for a beneficiary in the year of death and in the three years prior to death were identified. Descriptive statistical analyses were used for clinical and socio-demographic characteristics and to describe the costs. RESULTS: Of the 274 deaths included in this analysis, 92 occurred in 1998, 82 in 1999, and 100 in 2000. Most of the deceased were males (61.4%). Distribution in terms of type of health plan coverage (full versus hospitalization-only coverage) was similar among beneficiaries (53% had hospitalization only and 47% had full coverage). The total health plan expenditure in the last four years of life for the 274 decedents was US$ 26 300 283 (US$ 12 287 723 for beneficiaries with hospitalization-only and US$ 14 012 560 for those with full coverage). Expenditures increased progressively in the four years preceding death. About 70% of medical expenses for decedents in the four years of this analysis were incurred in the last year of life. CONCLUSION: Relatively large amounts of health care resources are used by Brazilian private health plan participants in their last year of life, suggesting that specific strategies are needed to optimize the allocation of medical care resources for these patients.

OBJETIVO: Examinar la utilización de los servicios de salud y los gastos asociados durante los últimos cuatro años de vida de brasileños con seguro privado de salud. MÉTODOS: Se emplearon los expedientes del seguro y los certificados de defunción de 274 beneficiarios de seguros de salud que murieron entre 1998 y 2000. Se identificaron los recursos utilizados para cada beneficiario durante el año que murió y los tres años anteriores. Mediante métodos estadísticos descriptivos se analizaron las características clínicas y sociodemográficas y se describieron los costos. RESULTADOS: De los 274 fallecidos analizados, 92 murieron en 1998, 82 en 1999 y 100 en 2000; la mayoría de ellos (61,4%) eran hombres. La distribución según el tipo de seguro de salud fue similar (cobertura total: 47%; solo cobertura de hospitalización: 53%). El gasto total del seguro de salud en los últimos cuatro años de vida de los 274 fallecidos fue de US$ 26 300 283 (US$ 12 287 723 para los beneficiarios con cobertura de hospitalización solamente y US$ 14 012 560 para los que tenían cobertura total). Los gastos aumentaron progresivamente en los cuatro años previos a la muerte. Cerca de 70% de los gastos médicos de los fallecidos en los cuatro años analizados correspondieron al último año de vida. CONCLUSIONES: Los brasileños con seguro médico privado utilizan una cantidad relativamente grande de recursos sanitarios en su último año de vida, por lo que se requieren estrategias específicas para optimizar la asignación de recursos de atención médica para estos pacientes.